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The immune synapse as a novel target for therapy

Nhà xuất bản : Springer

Năm xuất bản : 2008

Số phân loại : 616.079

Chủ đề : 1. Biomedical and Life Sciences ; Synapses ; Immune response|xMolecular aspects ; Immune response -- Regulation.. 2. Book.

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Tóm tắt :

The immune synapse can be compared to a molecular machine that controls T cell activation when getting in contact with an antigen-presenting cell (APC). The immune synapse is involved in the transfer of information across the T cell-APC junction. It plays an essential role in the control and nature of the immune response. In recent years several approaches have been developed to reprogramming the immune response by targeting molecules involved in the immune synapse. Monoclonal antibodies, such as the ones targeting the lymphocyte co-receptor, co-stimulatory and adhesion molecules

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https://repository.vnu.edu.vn/handle/VNU_123/23874