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  • Prescribing, dispensing and administration indicators to describe rational use of oral dosage forms of medicines given to children / Abarna Nadeshkumar;Gitanjali Sathiadas;Arunasalam Pathmeswaran;Shalini Sri Ranganathan
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Prescribing, dispensing and administration indicators to describe rational use of oral dosage forms of medicines given to children / Abarna Nadeshkumar;Gitanjali Sathiadas;Arunasalam Pathmeswaran;Shalini Sri Ranganathan

Tác giả : Abarna Nadeshkumar;Gitanjali Sathiadas;Arunasalam Pathmeswaran;Shalini Sri Ranganathan

Nhà xuất bản : World Health Organization. Regional Office for South-East Asia

Năm xuất bản : 2019

Chủ đề : 1. Medicine. 2. Journal / periodical articles.

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Background Owing to lack of indicators, researchers are compelled to use non-specific indicators toassess rational use of medicines in children. Thus, paediatric-specific issues are poorly described. Thisstudy aims to develop a set of indicators to describe rational use of oral dosage forms of medicinesgiven to children.Methods A modified RAND/UCLA Appropriateness Method was used. A comprehensive draft list of40 indicators was compiled, based on the results of a literature review. Twelve experts rated theseindicators in two rounds, using a nine-point Likert scale, first in an online survey, for clarity, necessityand scientific merit, and secondly in a face-to-face meeting, for necessity, feasibility and predictivevalue. An overall panel median score of ≥7 and agreement within the experts were used in indicators.The indicators were ranked independently by the research team and a final list of indicators wasprepared. These indicators were pilot-tested for acceptability and interrater reliability.Results Nine prescribing indicators, such as weight, appropriate dose and age-appropriate dosageform; five dispensing indicators, such as adequacy of labelling and inappropriate manipulation bypharmacists; and five administration indicators, such as inappropriate manipulation by parents and fullcompletion of dose, were finalized in the second round.Conclusion This novel approach has provided a set of indicators to describe the use of oral dosageforms of medicines given to children, which can be used by researchers as a supplement to the WorldHealth Organization’s drug use indicators when investigating rational use of medicines in children.
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https://iris.who.int/handle/10665/329497