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Community-based antimicrobial resistance screening among Syrian refugees and the host community in Turkey / World Health Organization. Regional Office for Europe

Tác giả : World Health Organization. Regional Office for Europe

Nhà xuất bản : World Health Organization. Regional Office for Europe

Năm xuất bản : 2021

Chủ đề : 1. Drug Resistance, Microbial. 2. Refugees. 3. Syria. 4. Turkey. 5. Technical documents.

Thông tin chi tiết

Tóm tắt :

45 p. The long-standing antimicrobial resistance (AMR) pandemic has proven difficult to resolve and is becoming more complex, especially through mass migration. This study aimed to determine the frequency of carriage of common types of antimicrobial-resistant bacteria in Syrian refugee and host communities in Turkey: extended-spectrum β-lactamase (ESBL), methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). The first stage involved the prospective collection of nasal swabs and stool samples from host communities and refugees between September 2020 and March 2021. The clinical samples were screened for the presence of ESBL-, MRSA- and VRE-positive Gram-negative bacteria using standard microbiological procedures. Antimicrobial-resistant bacterial isolates were tested by phenotypic analysis and genotypic analysis for resistance genes to determine the AMR mechanism. The study included a total of 3960 participants: 1435 (36.2%) samples were collected from Turkish citizens and 2525 (63.8%) from Syrian refugees. In all, 169 (6.7%) refugees and 46 (3.2%) Turkish citizens carried MRSA. The ESBL positivity rate was 17.9% in Syrian refugees and 14.3% in Turkish citizens. Carbapenemase activity was detected in three isolates from Syrian refugees. No VRE were detected in Syrian refugees or Turkish citizens. Rigorous data are needed for evidence-based management of the AMR pandemic. This community-based, large-scale study of AMR carriage in Syrian refugees and the host population in Turkey represents the first stage in this process.

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https://iris.who.int/handle/10665/350837