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Chlorophenols other than pentachlorophenol / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization / International Programme on Chemical Safety

Tác giả : International Programme on Chemical Safety

Nhà xuất bản : World Health Organization

Năm xuất bản : 1989

ISBN : 9241542934

Tùng thư : Environmental health criteria

Chủ đề : 1. Chlorophenols -- adverse effects toxicity.

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208 p. Evaluates the risks to human health and the environment posed by the widespread manufacturing and use of chlorophenols other than pentachlorophenol. These organic chemicals are biocides effective against a large number of organisms, including bacteria, algae, mollusks, acarids, fungi, and moulds. Although agricultural use is now restricted in a number of countries, chlorophenols continue to be widely applied in wood treatment and preservation and in the surface treatment of freshly cut logs and lumber. Smaller amounts are also used as additives to inhibit microbial growth in a range of products, including adhesives, oils, textiles, and pharmaceutical drugs. In view of the predominant uses of chlorophenols, a section linking levels in the environment to human exposure concentrates on the presence of these chemicals in drinking-water, foods and feed, and treated wood. Particular attention is given to levels found at sawmills, paper-mills, wood treatment facilities, and manufacturing sites. A review of data on kinetics and metabolism concludes that experimental animals accumulate chlorophenols mostly in the liver and kidney. The remaining sections evaluate effects on different organisms, health risks as identified in experimental studies and in vitro test systems, and human health effects as determined from both case reports of accidental poisoning and long-term studies of health effects, including possible carcinogenicity, associated with occupational exposures. While the degree of carcinogenic risk could not be determined, the report identifies the main symptoms of occupational exposure as irritation of the eye, nose and airway, dermatitis, chloracne, porphyria, abnormal liver function tests, changes in brain wave activity, and slowed visual reaction time. The book concludes with a series of recommendations concerning the production and disposal of chlorophenols and the measures needed to protect workers and the general public

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Thông tin dữ liệu nguồn

Thư viện	Ký hiệu xếp giá	Dữ liệu nguồn
Tổ chức y tế thế giới		https://iris.who.int/handle/10665/37123

Ldr		00025nam a2200024 a 4500
001		CLN240808979
020	__	$a9241542934
041	__	$aen
100	__	$aInternational Programme on Chemical Safety
245	__	$aChlorophenols other than pentachlorophenol / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization /$cInternational Programme on Chemical Safety
260	__	$bWorld Health Organization ,$c1989
490	__	$aEnvironmental health criteria $v93
520	__	$a208 p.
520	__	$aEvaluates the risks to human health and the environment posed by the widespread manufacturing and use of chlorophenols other than pentachlorophenol. These organic chemicals are biocides effective against a large number of organisms, including bacteria, algae, mollusks, acarids, fungi, and moulds. Although agricultural use is now restricted in a number of countries, chlorophenols continue to be widely applied in wood treatment and preservation and in the surface treatment of freshly cut logs and lumber. Smaller amounts are also used as additives to inhibit microbial growth in a range of products, including adhesives, oils, textiles, and pharmaceutical drugs. In view of the predominant uses of chlorophenols, a section linking levels in the environment to human exposure concentrates on the presence of these chemicals in drinking-water, foods and feed, and treated wood. Particular attention is given to levels found at sawmills, paper-mills, wood treatment facilities, and manufacturing sites. A review of data on kinetics and metabolism concludes that experimental animals accumulate chlorophenols mostly in the liver and kidney. The remaining sections evaluate effects on different organisms, health risks as identified in experimental studies and in vitro test systems, and human health effects as determined from both case reports of accidental poisoning and long-term studies of health effects, including possible carcinogenicity, associated with occupational exposures. While the degree of carcinogenic risk could not be determined, the report identifies the main symptoms of occupational exposure as irritation of the eye, nose and airway, dermatitis, chloracne, porphyria, abnormal liver function tests, changes in brain wave activity, and slowed visual reaction time. The book concludes with a series of recommendations concerning the production and disposal of chlorophenols and the measures needed to protect workers and the general public
650	_2	$aChlorophenols $xadverse effects toxicity
856	__	$uhttps://iris.who.int/handle/10665/37123
900		1
925		G
926		0
927		SH

Chlorophenols other than pentachlorophenol / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization / International Programme on Chemical Safety

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Chlorophenols other than pentachlorophenol / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization / International Programme on Chemical Safety

Thông tin dữ liệu nguồn

Tài liệu cùng tác giả

Principle for evaluating health risks to reproduction associated with exposure to chemicals

Arsenic and Arsenic compounds

Guidance document on evaluating and expressing uncertainty in hazard characterization / World Health Organization;International Programme on Chemical Safety

Inorganic chromium(VI) compounds / International Programme on Chemical Safety;Inter-Organization Programme for the Sound Management of Chemicals

Integrated risk assessment: report prepared for the WHO/UNEP/ILO International Programme on Chemical Safety / International Programme on Chemical Safety;International Workshop on Approaches to Integrated Risk Assessment (2001 : Ispra, Italy)

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