Thư viện tập trung - Thư viện điện tử

Sách, tuyển tập

Polychlorinated biphenyls and terphenyls = Difenilos y trifenilos policlorados / International Programme on Chemical Safety

Tác giả : International Programme on Chemical Safety

Nhà xuất bản : World Health Organization

Năm xuất bản : 1993

ISBN : 9241571403

Tùng thư : Environmental health criteria

Chủ đề : 1. Environmental Exposure -- adverse effects toxicity. 2. Environmental Pollutants. 3. Polychlorinated Biphenyls. 4. Polychloroterphenyl Compounds.

Chia sẻ

Thông tin chi tiết

Tóm tắt :

Evaluates the vast body of evidence demonstrating the serious threat to human and environmental health posed by polychlorinated biphenyls (PCBs). These chemicals, which are now ubiquitous in the environment, have been used commercially since 1930 as dielectric and heat-exchange fluids and in a variety of other applications. Over 1,300 studies were critically assessed. The book also contains a brief review of the limited data on polychlorinated terphenyls. A section devoted to the environmental behaviour of PCBs assesses the mechanisms by which these highly persistent chemicals, previously introduced into the environment, are gradually being redistributed towards increased contamination of the marine environment. For the general population, the most important sources of exposure are identified as food items and, for babies, breast-milk. The well-documented signs of poisoning in occupationally-exposed workers are also reviewed. A section devoted to the metabolic fate of PCBs cites evidence of accumulation in the liver and the adipose tissues of various organs, placental transport, fetal accumulation, and distribution to milk. The most extensive section, which runs some 100 pages, evaluates findings from studies of toxicity in experimental animals and in vitro systems. Findings suggest that PCBs are immunosuppressive and act as tumour promoters. An assessment of effects on humans draws upon studies of two large outbreaks of poisoning from contaminated food, and of occupational exposures. Concerning risks to the environment, the report cites reproductive failure in sea mammals as the most important hazard, further concluding that the predicted redistribution of residues towards the marine environment will pose an increasing hazard for sea mammals in the future. A review of the hazards of polychlorinated terphenyls concludes the report Summary and evaluation, conclusions and recommendations in French and SpanishSpanish 1st ed. issued as: Publicaci'on cient'ifica / Organizaci'on Panamericana de la Salud ; no. 387682 p.pol-1ed-French-1ed-Spanish-1ed-

Chia sẻ

Hiển thị MARC

Thông tin dữ liệu nguồn

Thư viện	Ký hiệu xếp giá	Dữ liệu nguồn
Tổ chức y tế thế giới		https://iris.who.int/handle/10665/38678

Ldr		00025nam a2200024 a 4500
001		CLN240810483
020	__	$a9241571403
041	__	$afr
041	__	$apl
041	__	$aes
041	__	$aja
041	__	$aen
100	__	$aInternational Programme on Chemical Safety
245	__	$aPolychlorinated biphenyls and terphenyls =$bDifenilos y trifenilos policlorados /$cInternational Programme on Chemical Safety
260	__	$bWorld Health Organization ,$c1993
490	__	$aEnvironmental health criteria $v140
520	__	$aSummary and evaluation, conclusions and recommendations in French and SpanishSpanish 1st ed. issued as: Publicaci'on cient'ifica / Organizaci'on Panamericana de la Salud ; no. 387682 p.pol-1ed-French-1ed-Spanish-1ed-
520	__	$aEvaluates the vast body of evidence demonstrating the serious threat to human and environmental health posed by polychlorinated biphenyls (PCBs). These chemicals, which are now ubiquitous in the environment, have been used commercially since 1930 as dielectric and heat-exchange fluids and in a variety of other applications. Over 1,300 studies were critically assessed. The book also contains a brief review of the limited data on polychlorinated terphenyls. A section devoted to the environmental behaviour of PCBs assesses the mechanisms by which these highly persistent chemicals, previously introduced into the environment, are gradually being redistributed towards increased contamination of the marine environment. For the general population, the most important sources of exposure are identified as food items and, for babies, breast-milk. The well-documented signs of poisoning in occupationally-exposed workers are also reviewed. A section devoted to the metabolic fate of PCBs cites evidence of accumulation in the liver and the adipose tissues of various organs, placental transport, fetal accumulation, and distribution to milk. The most extensive section, which runs some 100 pages, evaluates findings from studies of toxicity in experimental animals and in vitro systems. Findings suggest that PCBs are immunosuppressive and act as tumour promoters. An assessment of effects on humans draws upon studies of two large outbreaks of poisoning from contaminated food, and of occupational exposures. Concerning risks to the environment, the report cites reproductive failure in sea mammals as the most important hazard, further concluding that the predicted redistribution of residues towards the marine environment will pose an increasing hazard for sea mammals in the future. A review of the hazards of polychlorinated terphenyls concludes the report
650	_2	$aEnvironmental Exposure $xadverse effects toxicity
650	_2	$aEnvironmental Pollutants
650	_2	$aPolychlorinated Biphenyls
650	_2	$aPolychloroterphenyl Compounds
856	__	$uhttps://iris.who.int/handle/10665/38678
900		1
925		G
926		0
927		SH

Polychlorinated biphenyls and terphenyls = Difenilos y trifenilos policlorados / International Programme on Chemical Safety

Thông tin dữ liệu nguồn

Tài liệu cùng tác giả

WHO human health risk assessment toolkit: chemical hazards / World Health Organization;International Programme on Chemical Safety

Dermal exposure / World Health Organization;International Programme on Chemical Safety;Inter-Organization Programme for the Sound Management of Chemicals

Ultraviolet radiation / World Health Organization;International Programme on Chemical Safety

Carbon monoxide / World Health Organization;International Programme on Chemical Safety

Polychlorinated biphenyls and terphenyls / World Health Organization;International Programme on Chemical Safety

Lời ngỏ

Mục đích và phương châm hoạt động

Bản quyền