Thư viện tập trung - Thư viện điện tử

Sách, tuyển tập

Assessment of fracture risk and its application to screening for postmenopausal osteoporosis : report of a WHO study group [meeting held in Rome from 22 to 25 June 1992] / World Health Organization

Tác giả : World Health Organization

Nhà xuất bản : World Health Organization

Năm xuất bản : 1994

ISBN : 9241208430

Tùng thư : WHO technical report series

Chủ đề : 1. Bone Diseases. 2. Estrogen Replacement Therapy. 3. Fractures, Bone. 4. Menopause. 5. Osteoporosis, Postmenopausal.

Chia sẻ

Thông tin chi tiết

Tóm tắt :

129 p. An expert technical assessment of the many factors that influence the risk of osteoporotic fracture in postmenopausal women and thus need to be considered when planning the most effective public health interventions. In view of growing awareness of the need to prevent and treat postmenopausal osteoporosis, the book aims to resolve several controversies concerning the usefulness of screening programmes, the appropriate target populations, the most effective methods for predicting fracture risk, techniques for assessment, and the comparative effectiveness of currently available preventive and therapeutic interventions. More than 450 references to the literature are included. The report opens with a detailed review of what is known about osteoporosis, the criteria for establishing diagnosis, the value of bone mineral density measurements as diagnostic and prognostic tools, factors that influence the morbidity and mortality caused by fractures at different sites, and the physiological determinants of bone loss and fracture risk. A review of the epidemiology of osteoporotic fractures is used to determine the size of the public health problem, to identify appropriate target populations for screening, and to define intervention thresholds. A large part of the report is devoted to a review of the advantages and limitations of three candidate methods for predicting future fracture risk: assessment of bone mass, assessment of bone loss, and clinical assessment of risk factors. Information on non-invasive physical techniques for bone mass assessment is especially detailed. Currently available techniques are described and discussed in terms of their performance characteristics, safety, accuracy, and suitability for use as screening tools. The report also evaluates various biochemical and other methods for the assessment of bone loss, lists the currently known risk factors and protective factors, and considers whether these factors can be used to identify high-risk individuals. A section devoted to the risks and benefits of intervention evaluates the efficacy and safety of hormone replacement therapy, using estro-gens alone or estrogens combined with progestogens, and other currently available interventions, including the use of calcium, calcitonins, and bisphosphonates. Particular attention is given to the assessment of evidence that estrogen replacement therapy might increase the risk of certain cancers and decrease the risk of morbidity and mortality from cardiovascular disease. The final section, on screening, reaches a number of important conclusions concerning the value, aims, target population, assessment methods, interventions, and organization of screening programmes for postmenopausal osteoporosis. These conclusions form the basis for several practical and technical recommendations useful to public health authorities as well as to clinicians seeking guidance on safe and effective ways to prevent osteoporotic fractures

Chia sẻ

Hiển thị MARC

Thông tin dữ liệu nguồn

Thư viện	Ký hiệu xếp giá	Dữ liệu nguồn
Tổ chức y tế thế giới		https://iris.who.int/handle/10665/39142

Ldr		00025nam a2200024 a 4500
001		CLN240810927
020	__	$a9241208430
041	__	$aen
041	__	$ait
100	__	$aWorld Health Organization
245	__	$aAssessment of fracture risk and its application to screening for postmenopausal osteoporosis : report of a WHO study group [meeting held in Rome from 22 to 25 June 1992] /$cWorld Health Organization
260	__	$bWorld Health Organization ,$c1994
490	__	$aWHO technical report series $v843
520	__	$a129 p.
520	__	$aAn expert technical assessment of the many factors that influence the risk of osteoporotic fracture in postmenopausal women and thus need to be considered when planning the most effective public health interventions. In view of growing awareness of the need to prevent and treat postmenopausal osteoporosis, the book aims to resolve several controversies concerning the usefulness of screening programmes, the appropriate target populations, the most effective methods for predicting fracture risk, techniques for assessment, and the comparative effectiveness of currently available preventive and therapeutic interventions. More than 450 references to the literature are included. The report opens with a detailed review of what is known about osteoporosis, the criteria for establishing diagnosis, the value of bone mineral density measurements as diagnostic and prognostic tools, factors that influence the morbidity and mortality caused by fractures at different sites, and the physiological determinants of bone loss and fracture risk. A review of the epidemiology of osteoporotic fractures is used to determine the size of the public health problem, to identify appropriate target populations for screening, and to define intervention thresholds. A large part of the report is devoted to a review of the advantages and limitations of three candidate methods for predicting future fracture risk: assessment of bone mass, assessment of bone loss, and clinical assessment of risk factors. Information on non-invasive physical techniques for bone mass assessment is especially detailed. Currently available techniques are described and discussed in terms of their performance characteristics, safety, accuracy, and suitability for use as screening tools. The report also evaluates various biochemical and other methods for the assessment of bone loss, lists the currently known risk factors and protective factors, and considers whether these factors can be used to identify high-risk individuals. A section devoted to the risks and benefits of intervention evaluates the efficacy and safety of hormone replacement therapy, using estro-gens alone or estrogens combined with progestogens, and other currently available interventions, including the use of calcium, calcitonins, and bisphosphonates. Particular attention is given to the assessment of evidence that estrogen replacement therapy might increase the risk of certain cancers and decrease the risk of morbidity and mortality from cardiovascular disease. The final section, on screening, reaches a number of important conclusions concerning the value, aims, target population, assessment methods, interventions, and organization of screening programmes for postmenopausal osteoporosis. These conclusions form the basis for several practical and technical recommendations useful to public health authorities as well as to clinicians seeking guidance on safe and effective ways to prevent osteoporotic fractures
650	_2	$aOsteoporosis, Postmenopausal
650	_2	$aBone Diseases
650	_2	$aEstrogen Replacement Therapy
650	_2	$aFractures, Bone
650	_2	$aMenopause
856	__	$uhttps://iris.who.int/handle/10665/39142
900		1
925		G
926		0
927		SH

Assessment of fracture risk and its application to screening for postmenopausal osteoporosis : report of a WHO study group [meeting held in Rome from 22 to 25 June 1992] / World Health Organization

Thông tin dữ liệu nguồn

Tài liệu cùng tác giả

WHO: Ebola situation report 14 October 2015 / World Health Organization

Seasonal influenza vaccine use in low and middle income countries in the tropics and subtropics: a systematic review / Hirve, Siddhivinayak;World Health Organization

WHO annual meeting with diagnostic manufacturers and stakeholders: global forecasts of diagnostic demand for 2014-2018, Geneva Switzerland / World Health Organization

Global antimicrobial resistance surveillance system: manual for early implementation / World Health Organization

WHO: Ebola situation report 7 October 2015 / World Health Organization

Lời ngỏ

Mục đích và phương châm hoạt động

Bản quyền