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Prevalence of HCV/HIV co-infection among haemophilia patients in Baghdad / Al Kubaisy, W.A.;Al Naib, K.T.;Habib, M.A.

Tác giả : Al Kubaisy, W.A.;Al Naib, K.T.;Habib, M.A.

Năm xuất bản : 2006

Chủ đề : 1. Genotype. 2. Hemophilia A. 3. Hepatitis C. 4. HIV Seropositivityb. 5. Polymerase Chain Reaction. 6. Serotyping.

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264-269 To estimate the seroprevalence of HCV infection among HIV-infected haemophiliacs and to demonstrate the most prevalent HCV genotype, 47 HIV-infected haemophilia patients were screened for anti-HCV antibodies. By performing polymerase chain reaction and DNA enzyme immunoassay, HCV-RNA was detected with subsequent genotyping. Seroprevalence of anti-HCV antibodies was 66.0%. Of 31 HCV/HIV co-infected patients, 21 [67.7%] had no history of blood transfusion. We detected 4 HCV genotypes: 1a, 1b, 4 and 4 mixed with 3a, HCV-1b being the most frequent. Contaminated factor VIII [clotting factor] could be responsible for disease acquisition
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https://iris.who.int/handle/10665/117081