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[Diagnosis of pulmonary tuberculosis: evaluation of the TB IgA EIA assay in Morroco] / Baassi, L.;El Fenniri, L.;Bourkkadi, J.;Benjalloun, C.;Cherkaoui, I.;El Iraki, G.;Benkouka, F.;Benjouad, A.;El Aouad, R.

Tác giả : Baassi, L.;El Fenniri, L.;Bourkkadi, J.;Benjalloun, C.;Cherkaoui, I.;El Iraki, G.;Benkouka, F.;Benjouad, A.;El Aouad, R.

Năm xuất bản : 2007

Chủ đề : 1. Antibodies, Bacterial. 2. Enzyme-Linked Immunosorbent Assay. 3. Immunoglobulin A. 4. Mycobacterium tuberculosis. 5. Tuberculosis, Pulmonary.

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Tóm tắt :

72-78 We analysed 2 evaluation lots of the TB IgA EIA test in pulmonary tuberculosis patients [TBp]. Sera were obtained from 345 TBp, 18 healthy subjects [HS], 28 subjects in contact with tuberculous patients [CS] and 16 non-tuberculous lung disease patients [N-TB] for the first evaluation lots and 302 TBp, 60 HS, 21 CS and 18 N-TB for the second. IgA titres against p-90 antigen with the second evaluation lot were significantly higher than the first evaluation lot. With the second evaluation lots, the sensitivity was 78.8% whereas with the first evaluation lot, the sensitivity was 75.9%. Specificity for the first and second evaluation lots was 50% and 70.7% respectively. The sensitivity of this test is still not satisfactory to establish pulmonary tuberculosis diagnosis

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https://iris.who.int/handle/10665/117226