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Platelet storage time and cytokine [IL-2R, IL-8, TNF-alpha] levels / Bayraktarog lu, Z.;Yilmaz, N.;Cicek, H.K.;Karafak, A.;Gul, E.
Tác giả : Bayraktarog lu, Z.;Yilmaz, N.;Cicek, H.K.;Karafak, A.;Gul, E.
Năm xuất bản : 2007
Chủ đề : 1. Cryopreservation. 2. Interleukin-2 Receptor alpha Submit. 3. Interleukin-8. 4. Leukocyte Count. 5. Leukocytes. 6. Plateletpheresis. 7. Tumor Necrosis Factor-alpha.
Thông tin chi tiết
Tóm tắt : | 79-84 This study investigated whether cytokine accumulation in plasma of platelet concentrates obtained from single apheresis donors was beyond the acceptable limits of white blood cell contamination at different storage time-points. Samples were obtained from 11 voluntary apheresis donors. All products were heavily contaminated with leukocytes. Sampling times from stored platelets were 0, 1, 3, 5 days respectively. Platelet, white blood cell counts and cytokines [IL-2R, IL-8 and TNF-alpha] were measured. The study found significant cytokine accumulation during 5 days of storage time in leukocyte contaminated platelet concentrates, suggesting that the platelet storage time has an effect on IL-2R levels |
Thông tin dữ liệu nguồn
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https://iris.who.int/handle/10665/117227 |