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  • Pattern of congenital malformations in consanguineous versus nonconsanguineous marriages in Kashan, Islamic Republic of Iran / Mosayebi, Z.;Movahedian, A.H.
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Pattern of congenital malformations in consanguineous versus nonconsanguineous marriages in Kashan, Islamic Republic of Iran / Mosayebi, Z.;Movahedian, A.H.

Tác giả : Mosayebi, Z.;Movahedian, A.H.

Năm xuất bản : 2007

Chủ đề : 1. Abnormalities. 2. Congenital Abnormalities. 3. Consanguinity. 4. Prospective Studies. 5. Sex Distribution.

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868-875 This study determined the types, patterns and prevalence of congenital malformation among the offspring of consanguineous and nonconsanguineous parents. In this prospective study of 3529 neonates delivered alive during a 1-year period, 109 had congenital malformations [3.09/1000 live births]. The rate of congenital malformation was 2.0% among neonates from nonconsanguineous marriages and 7.0% from consanguineous marriages. The most common malformations were genitourinary [32.1%], musculoskeletal [22.0%] and cardiovascular [14.7%]. Of the total malformed infants, 8.3% died within the neonatal period. Male infants were at greater risk for birth malformations. A history of congenital malformation was more common in siblings of consanguineous than nonconsanguineous marriages
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https://iris.who.int/handle/10665/117324