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  • Characterization of Mycobacterium tuberculosis in Syrian patients by double-repetitive-element polymerase chain reaction / Rahmo, A.;Hamze, M.
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Characterization of Mycobacterium tuberculosis in Syrian patients by double-repetitive-element polymerase chain reaction / Rahmo, A.;Hamze, M.

Tác giả : Rahmo, A.;Hamze, M.

Năm xuất bản : 2010

Chủ đề : 1. Genotype. 2. Microbial Sensitivity Tests. 3. Mycobacterium tuberculosis. 4. Polymerase Chain Reaction. 5. Tuberculosis, Multidrug-Resistant.

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820-830 The role of previous treatment in the dynamics of tuberculosis transmission has not been adequately investigated. Mycobacterium tuberculosis isolates from previously treated patients [n = 88] from all regions of Syrian Arab Republic were characterized in terms of antibiotic sensitivity and genotyping using double-repetitive-element polymerase chain reaction [DRE-PCR] method for the proximity of the repetitive DNA elements IS6110 [a mobile genetic element] and PGRS. The 88 isolates resulted in 59 different DRE-PCR patterns. Correlations related to age, sex, region, sensitivity and genotype were examined. All regions of the country showed high levels of genotype diversity, suggesting a low level of transmission of M. tuberculosis strains in previously treated patients
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https://iris.who.int/handle/10665/117945