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Eosinophilic cationic protein: is it useful in assessing control of childhood asthma? / Zedan, M.;Settin, A.;El Chennawi, F.;El Desouky, T.;Nasef, N.;Fouda, A.

Tác giả : Zedan, M.;Settin, A.;El Chennawi, F.;El Desouky, T.;Nasef, N.;Fouda, A.

Năm xuất bản : 2010

Chủ đề : 1. Asthma. 2. Case-Control Studies. 3. Cross-Sectional Studies. 4. Eosinophil Cationic Protein. 5. Eosinophils.

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Tóm tắt :

1045-1049 This study evaluated peripheral eosinophil and serum eosinophilic cationic protein [s-ECP] levels as markers of asthma control. A total of 38 children with asthma [16 controlled and 22 partially controlled] were compared with 16 age- and sex-matched healthy children. Total asthma cases had higher eosinophil counts and s-ECP levels than healthy children and partially controlled asthmatics had significantly higher levels of both markers than controlled asthmatics. Controlled asthma cases showed non-significant changes in both parameters versus healthy children. A negative correlation was noted between degree of asthma control and both eosinophil counts and s-ECP levels [r = -0.60 and -0.75 respectively]. s-ECP as well as peripheral eosinophil count may be helpful in the assessment of asthma control

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https://iris.who.int/handle/10665/118001