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  • Fluoroquinolone and macrolide co-resistance in clinical isolates of Campylobacter species: a 15-year study in Karachi, Pakistan / Irfan, S.;Ahmad, A.;Guhar, D.;Khan, E.;Malik., F.;Mahmood, S.;Zafar, A.
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Fluoroquinolone and macrolide co-resistance in clinical isolates of Campylobacter species: a 15-year study in Karachi, Pakistan / Irfan, S.;Ahmad, A.;Guhar, D.;Khan, E.;Malik., F.;Mahmood, S.;Zafar, A.

Tác giả : Irfan, S.;Ahmad, A.;Guhar, D.;Khan, E.;Malik., F.;Mahmood, S.;Zafar, A.

Năm xuất bản : 2010

Chủ đề : 1. Campylobacter. 2. Drug Resistance, Bacterial. 3. Fluoroquinolones. 4. Macrolides. 5. Microbial Sensitivity Tests. 6. Retrospective Studies.

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1226-1230 Fluoroquinolone and macrolide antibiotics are generally considered as first-line drugs for the treatment of severe campylobacteriosis. This study was conducted to analyse the trend of erythromycin and ofloxacin resistance among Campyiobacter spp. isolated from stool specimens over a period of 15 years [1992-2007] at The Aga Khan University clinical laboratory in Karachi, Pakistan. A total of 83 396 stool specimens were processed, with a 14% isolation rate for enteric pathogens. The isolation rate of Campylobacter spp. was low during 1992-93 [6%-13%], peaked in 1996 [46%], then ranged from 20% to 40%. We report a rising trend in ofloxacin resistance, re-emergence of erythromycin resistance and indications of co-resistance to both drugs in clinical isolates of Campylobocter spp.
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https://iris.who.int/handle/10665/118058