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Epidemiological and biologic profile of breast cancer in Fez-Boulemane, Morocco / Abbass, F.;Bennis, S.;Znati, K.;Akasbi, Y.;Amrani, J.K.;El Mesbahi, O.;Amarti, M.

Tác giả : Abbass, F.;Bennis, S.;Znati, K.;Akasbi, Y.;Amrani, J.K.;El Mesbahi, O.;Amarti, M.

Năm xuất bản : 2011

Chủ đề : 1. Awareness. 2. Breast Neoplasms. 3. Immunohistochemistry. 4. Prognosis. 5. Retrospective Studies.

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Tóm tắt :

930-936 In a retrospective study of 265 patients with breast cancer over 3 years [January 2007-September 2009] we examined the epidemiological profile of breast cancer to determine the impact of biological and prognostic factors on survival over 3 years and on the epidemiology of this cancer. Estrogen [RE], progesterone [RP] and human epidermal growth factor receptors [HER2] were evaluated and RE/RP/HER2 status determined. The patients were young [median age 45 years]. Invasive tumours were found in 95.5% of the women. The average tumour size was big [3.6 [SD 2.6] cm] and only 14% were histological grade I. Large tumour size and high histological grade were independent of patient's age. Overall survival at 3 years was only 49% for the RE-/RP-/HER2- subtype and 75% for the RE-/RP-/HER2+ subtype, while it was 96% for the RE+/RP+/HER2- subtype. The young age, large tumour size and high histological grade in our population suggest a lack of awareness of women about breast cancer

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https://iris.who.int/handle/10665/118224