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Does the rapid healing of duodenal ulcers mean longer remissions? / Ahmed, W.;Qureshi, H.;Zuberi, S.J.;Alam, S.E.

Tác giả : Ahmed, W.;Qureshi, H.;Zuberi, S.J.;Alam, S.E.

Năm xuất bản : 1998

Chủ đề : 1. Anti-Ulcer Agents. 2. Duodenal Ulcer. 3. Endoscopy, Digestive System. 4. Follow-Up Studies. 5. Histamine H2 Antagonists. 6. Misoprostol. 7. Proton Pump Inhibitors. 8. Recurrence. 9. Remission Induction. 10. Treatment Outcome. 11. Wound Healing.

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554-559 A study was conducted to test the response to therapy and the relapse rates of endoscopically-confirmed duodenal ulcers. Endoscopy to check for healing was performed at 4 and 8 weeks in cases receiving H2-blockers and misoprostol and at 14 and 28 days in cases receiving a proton pump inhibitor. Endoscopy was repeated at 1, 3, 6 and 12 months to check for relapses. Healing rates were 61%-77% and 75%-85% at 4 and 8 weeks in the group receiving H2-blockers and misoprostol. Healing rates were 68% and 100% at days 14 and 28 with the proton pump inhibitor. The relapse rates within 3 months were 72%-86% and 100% respectively. This study indicates that the faster the ulcer healed, the earlier the relapse occurred
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https://iris.who.int/handle/10665/118463