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Factors associated with treatment default by tuberculosis patients in Fez, Morocco / Slama, K.;Tachfouti, N.;Obtel, M.;Nejjari, C.

Tác giả : Slama, K.;Tachfouti, N.;Obtel, M.;Nejjari, C.

Năm xuất bản : 2013

Chủ đề : 1. Alcohols. 2. Case-Control Studies. 3. Knowledge. 4. Logistic Models. 5. Questionnaires. 6. Recurrence. 7. Smoking. 8. Tuberculosis.

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Tóm tắt :

687 - 693 Interruption in tuberculosis [TB] treatment still remains the most important challenge for control of the disease. This study aimed to identify the determinants of TB treatment default in Fez, Morocco. A 1:2 pair-matched case-control study was carried out in the TB control units in Fez. Cases were defaulters to TB treatment and were matched by age and sex to non-defaulters [controls]. Of the 320 patients [108 defaulters, 212 controls], 80.6% were male. The main reason for defaulting reported by patients was the sensation of being cured. Predictive factors for treatment default in the multivariate conditional logistic regression analysis, were: relapsed case [adjusted OR = 4.49; 95% CI: 1.87-10.8], current smoking [aOR = 2.10; 95% CI: 1.07-4.14], alcohol use [aOR = 2.92; 95% CI: 1.04-8.19], being more than 30 minutes away from the health centre [aOR = 3.34; 95% CI: 1.06-10.5] and perception of having received insufficient explanation about the disease [aOR = 2.87; 95% CI: 1.53-5.36]. The rate of defaulting in Fez can be lowered through targeted and realistic measures

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https://iris.who.int/handle/10665/118526