loading
  • Trang chủ
  • Sách, tuyển tập
  • Cartilage proteoglycan aggrecan as a predictor of joint damage in juvenile rheumatoid arthritis / El Sayed, Z.A.;Saleh, M.T.;Al Wakkad, A.S.;Sherief, L.S.;Nasr El Din, A.M.
Sách, tuyển tập

Cartilage proteoglycan aggrecan as a predictor of joint damage in juvenile rheumatoid arthritis / El Sayed, Z.A.;Saleh, M.T.;Al Wakkad, A.S.;Sherief, L.S.;Nasr El Din, A.M.

Tác giả : El Sayed, Z.A.;Saleh, M.T.;Al Wakkad, A.S.;Sherief, L.S.;Nasr El Din, A.M.

Năm xuất bản : 2001

Chủ đề : 1. Aggrecans. 2. Arthritis, Juvenile Rheumatoid. 3. Collagen Diseases. 4. Extracellular Matrix Proteins. 5. Proteoglycans. 6. Severity of Illness Index. 7. Synovial Fluid.

Chia sẻ

Thông tin chi tiết

Tóm tắt :

992-1003 Aggrecan was measured in the sera of 31 children with juvenile rheumatoid arthritis and in the synovial fluid of 10 of them. Patients were evaluated at baseline and 3 months later. Radiographs were repeated also after 1 year. As comparison, 15 apparently healthy children with no disease and 10 children with arthritis due to other collagen vascular diseases were studied. Baseline serum aggrecan was significantly higher in juvenile rheumatoid arthritis patients compared to controls and other patients. On re-evaluation, a significant drop in serum aggrecan from baseline values coincided with a significant drop in clinical and laboratory indices of active inflammation. Serum aggrecan can help to assess the extent of cartilage destruction and is useful as a prognostic tool to predict joint damage in patients with juvenile rheumatoid arthritis
Chia sẻ


Hiển thị MARC

 Thông tin dữ liệu nguồn

 Thư viện  Ký hiệu xếp giá  Dữ liệu nguồn
Tổ chức y tế thế giới
https://iris.who.int/handle/10665/119118