Reduction of clinical tuberculosis in HIV-infected males with isoniazid prophylaxis / Alaei, K.;Alaei, A.;Mansouri, D.
Tác giả : Alaei, K.;Alaei, A.;Mansouri, D.
Năm xuất bản : 2002
Chủ đề : 1. AIDS-Related Opportunistic. 2. Antitubercular Agents. 3. Chemoprevention. 4. Isoniazid. 5. Prevalence. 6. Prisoners. 7. Prospective Studies. 8. Skin Tests. 9. Substance Abuse, Intravenous. 10. Tuberculin. 11. Tuberculosis.
Thông tin chi tiết
Tóm tắt : | 754-757 Isoniazid [INH] chemoprophylaxis has a positive impact on the development of clinical tuberculosis. Due to the increased prevalence of tuberculosis among HIV-infected individuals, we evaluated the effect of INH on the prevention of clinical tuberculosis in HIV-infected patients. We administered 300 mg of INH daily to 246 HIV-infected, tuberculin skin test-positive patients for 12 months. During 3 years of follow-up, 41 participants died and 94 were lost to follow up. Of the 111 patients followed for the 3 years, 12 developed tuberculosis which is lower than might be expected in an untreated group. INH prophylaxis appears to be an effective method to prevent clinical tuberculosis among HIV-infected, tuberculin skin test-positive patients |
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https://iris.who.int/handle/10665/119224 |