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Frequency of haemoglobinopathies and glucose-6-phosphate dehydrogenase deficiency in Basra / Hassan, M.K.;Taha, J.Y.;Al Naama, L.M.;Widad, N.M.;Jasim, S.N.

Tác giả : Hassan, M.K.;Taha, J.Y.;Al Naama, L.M.;Widad, N.M.;Jasim, S.N.

Năm xuất bản : 2003

Chủ đề : 1. Epidemiology, Molecular. 2. Fetal Hemoglobin. 3. Gene Frequency. 4. Genetic Counseling. 5. Genetic Screening. 6. Glucosephosphate Dehydrogenase Deficiency. 7. Hemoglobin C Disease. 8. Hemoglobinopathies.

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Tóm tắt :

45-54 Basra, southern Iraq, was mapped for haemoglobinopathies and glucose-6-phosphate dehydrogenase [G6PD] deficiency. Of 1064 couples aged 14-60 years recruited from the Public Health Laboratory, 49 had beta-thalassaemia trait, 69 had sickle-cell trait, 2 had haemoglobin D trait, 2 had haemoglobin C trait and 1 had high persistent fetal haemoglobin. Carriers of major beta-globin disorders comprised 11.48%. G6PD deficiency was detected in 133 individuals [12.5%]. Only 10 couples [0.94%] were at risk of having children affected with either sickle-cell disease or beta-thalassaemia major. These defects constitute a real health problem and necessitate a management plan and public health education for early diagnosis and therapy

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https://iris.who.int/handle/10665/119242