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Effect of gender on reporting of MMR adverse events in Saudi Arabia / Khalil, M.K.;Al Mazrou, Y.Y.;Al Ghamdi, Y.S.;Tumsah, S.;Al Jeffri, M.;Meshkhas, A.

Tác giả : Khalil, M.K.;Al Mazrou, Y.Y.;Al Ghamdi, Y.S.;Tumsah, S.;Al Jeffri, M.;Meshkhas, A.

Năm xuất bản : 2003

Chủ đề : 1. Adverse Drug Reaction Reporting Systems. 2. Data Collection. 3. Drug Hypersensitivity. 4. Fever. 5. Immunization Programs. 6. Metabolic Clearance Rate. 7. Sex Distribution. 8. Vaccines.

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Tóm tắt :

152-158 We evaluated the safety of a measles-mumps-rubella [MMR] immunization campaign for Saudi children [age range: 6-13 years] and gender differences in reporting post-MMR adverse events. After vaccinations were administered, we monitored 160 schools for 14 days and 19 hospitals in the 8 cities under study for 10 weeks. Incidence rates were: all MMR adverse events, 26.5/10,000 MMR vaccines [significantly higher in females than males]; Urabe strain aseptic meningitis, 1.0/295,000; fever, 40.2/10,000 [females] and 0.9/10,000 [males]; and parotitis, 5.4/10,000 [females] and 0.9/10,000 [males]. Combined MMR vaccine containing the Urabe mumps strain was safe for children aged 6-13 years. Gender differences regarding reactogenicity were evident and should be considered when designing future studies

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https://iris.who.int/handle/10665/119256