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  • Student screening for inherited blood disorders in Bahrain / Al Arrayed, S.;Hafadh, N.;Amin, S.;Al Mukhareq, H.;Sanad, H.
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Student screening for inherited blood disorders in Bahrain / Al Arrayed, S.;Hafadh, N.;Amin, S.;Al Mukhareq, H.;Sanad, H.

Tác giả : Al Arrayed, S.;Hafadh, N.;Amin, S.;Al Mukhareq, H.;Sanad, H.

Năm xuất bản : 2003

Chủ đề : 1. Anemia, Sickle Cell. 2. Consanguinity. 3. Genetic Counseling. 4. Glucosephosphate Dehydrogenase. 5. Health Education. 6. Health Services Needs and Demand. 7. Hemoglobin C Disease. 8. Hemoglobinopathies. 9. Mutation.

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344-352 In Bahrain and neighbouring countries inherited disorders of haemoglobin, i.e. sickle-cell disease, thalassaemias and glucose-6-phosphate dehydrogenase [G6PD] deficiency, are common. As part of the National Student Screening Project to determine the prevalence of genetic blood disorders and raise awareness among young Bahrainis, we screened 11th-grade students from 38 schools [5685 students], organized lectures and distributed information about these disorders. Haemoglobin electrophoresis, high performance liquid chromatography, blood grouping and G6PD deficiency testing were performed. Prevalences were: 1.2% sickle-cell disease; 13.8% sickle-cell trait; 0.09% beta-thalassaemia; 2.9% beta-thalassaemia trait; 23.2% G6PD deficiency; 1.9% G6PD deficiency carrier. Health education, carrier screening and premarital counselling remain the best ways to reduce disease incidence with potentially significant financial savings and social and health benefits
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https://iris.who.int/handle/10665/119283