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  • Field evaluation of latex agglutination test for detecting urinary antigens in visceral leishmaniasis in Sudan / El Safi, S.H.;Abdel Haleem, A.;Hammad, A.;El Basha, I.;Omer, A.;Kareem, H.G.;Boelaert, M.;Chance, M.;Hommel, M.
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Field evaluation of latex agglutination test for detecting urinary antigens in visceral leishmaniasis in Sudan / El Safi, S.H.;Abdel Haleem, A.;Hammad, A.;El Basha, I.;Omer, A.;Kareem, H.G.;Boelaert, M.;Chance, M.;Hommel, M.

Tác giả : El Safi, S.H.;Abdel Haleem, A.;Hammad, A.;El Basha, I.;Omer, A.;Kareem, H.G.;Boelaert, M.;Chance, M.;Hommel, M.

Năm xuất bản : 2003

Chủ đề : 1. Antigens, Protozoan. 2. Case-Control Studies. 3. Child, Preschool. 4. Endemic Diseases. 5. Enzyme-Linked Immunosorbent Assay. 6. Fluorescent Antibody Technique, Indirect. 7. Immunoblotting. 8. Latex Fixation Tests. 9. Leishmania donovani. 10. Leishmaniasis, Visceral. 11. Parasitology.

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Tóm tắt :

844-855 A latex agglutination test to detect urinary antigens for visceral leishmaniasis [VL] was studied. In 204 patients with suspected VL, KAtex had a sensitivity of 95.2% with good agreement with microscopy smears but poor agreement with 4 different serology tests. It was also positive in 2 confirmed VL cases co-infected with HIV. In all KAtex-positive confirmed cases actively followed up after treatment, the test became negative 1 month after completion of treatment. While KAtex had a specificity of 100% in healthy endemic and non-endemic controls, the direct agglutination test [DAT] was positive in 14% of the KAtex-negative healthy endemic controls. KAtex is a simple addition to the diagnostics of VL particularly at field level and as a complementary test for the diagnosis of VL in smear-negative cases with positive DAT results
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https://iris.who.int/handle/10665/119338