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  • Visceral leishmaniasis in the Syrian Arab Republic: early detection using rK39 / Al Nahhas, S.;Shabaan, M.;Hammoud, L.;Al Taweel, A.;Al Jorf, S.
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Visceral leishmaniasis in the Syrian Arab Republic: early detection using rK39 / Al Nahhas, S.;Shabaan, M.;Hammoud, L.;Al Taweel, A.;Al Jorf, S.

Tác giả : Al Nahhas, S.;Shabaan, M.;Hammoud, L.;Al Taweel, A.;Al Jorf, S.

Năm xuất bản : 2003

Chủ đề : 1. Antigens, Protozoan. 2. Cross-Sectional Studies. 3. Enzyme-Linked Immunosorbent Assay. 4. Health Services Accessibility. 5. Health Surveys. 6. Leishmania donovani. 7. Leishmaniasis, Visceral. 8. Mass Screening. 9. Medically Underserved Area. 10. Protozoan Proteins. 11. Reagent Strips. 12. Sensitivity and Specificity.

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Tóm tắt :

856-862 Leishmaniasis causes significant morbidity and mortality in areas where it is endemic. A seroprevalence survey was conducted in 2 endemic villages in Daraa, Syrian Arab Republic, where 80 out of 345 children [23.2%] tested positive for visceral leishmaniasis [VL] using rK39 dipstick test. Only 10 cases were symptomatic [12.5%], and 27.5% were positive by ELISA test. All the sera [N = 138] obtained from the control village were negative. Of the rK39 initially positive cases, 52 had seroconverted to negative 9 months later, 55 remained ELISA negative, and none developed the full-blown disease. Being faster and less expensive than other diagnostic tests, rK39 is a rapid, sensitive and specific diagnostic tool for symptomatic cases of VL in remote areas with poor accessibility to health services
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https://iris.who.int/handle/10665/119340