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  • Measles seroepidemiology among adolescents and young adults: response to revaccination / Saffar, M.J.;Al Raza Amiri, M.;Ajami, A.;Baba Mahmoodi, F.;Khalilian, A.R.;Vahidshahi, C.;Shamsizadeh, A.
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Measles seroepidemiology among adolescents and young adults: response to revaccination / Saffar, M.J.;Al Raza Amiri, M.;Ajami, A.;Baba Mahmoodi, F.;Khalilian, A.R.;Vahidshahi, C.;Shamsizadeh, A.

Tác giả : Saffar, M.J.;Al Raza Amiri, M.;Ajami, A.;Baba Mahmoodi, F.;Khalilian, A.R.;Vahidshahi, C.;Shamsizadeh, A.

Năm xuất bản : 2006

Chủ đề : 1. Measles. 2. Measles Vaccine. 3. Monitoring, Immunologic. 4. Serologic Tests.

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573-581 We evaluated the seroprevalence of measles antibody and response to measles re-immunization in 590 previously vaccinated adolescents and young adults; 263 were seronegative. To differentiate between primary and secondary vaccine failure, anti- measles IgM and IgG titres were assessed again 2- 4 weeks after revaccination in 144 [105 seronegative, 39 seropositive] individuals: 75 seronegative participants responded to revaccination anamnestically [P < 0.001] and developed immunity 11 also showed IgM response [probably primary vaccine failure immunity]; 38 seropositive participants, remained seroprotected without significant increase in antibody titre [P = 0.577]. Primary vaccine failure was 4.7%; secondary vaccine failure was 27.1%. After revaccination, 87.3% were seroprotected
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https://iris.who.int/handle/10665/117121