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  • T-cell cytokine production and endothelial dysfunction in type 2 diabetic patients with nephropathy / Kamel, L.;Morsy, A.;El Shamaa, A.
Sách, tuyển tập

T-cell cytokine production and endothelial dysfunction in type 2 diabetic patients with nephropathy / Kamel, L.;Morsy, A.;El Shamaa, A.

Tác giả : Kamel, L.;Morsy, A.;El Shamaa, A.

Năm xuất bản : 2009

Chủ đề : 1. Creatinine. 2. Diabetes Mellitus, Type 2. 3. Diabetic Nephropathies. 4. Endothelium. 5. E-Selectin. 6. Interferon-gamma. 7. Interleukin-10. 8. Renal Dialysis. 9. T-Lymphocytes.

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807-816 This study assessed changes in serum levels of cytokines IFNgamma and IL-10 [biomarkers of inflammatory changes] and soluble biomarkers sICAM-1 and sE-selectin [biomarkers of endothelial dysfunction] in diabetic patients with and without nephropathy. IFNgamma and IL-10 were significantly elevated in patients with diabetic nephropathy [DN] and end-stage renal disease [ESRD] compared with controls and diabetic patients without DN. IFNgamma and IL-10 levels were significantly increased after haemodialysis. sICAM-1 and sE-selectin were significantly higher in diabetic, DN and ESRD groups compared with controls, and sICAM-1 but not sE-selectin was increased after haemodialysis
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https://iris.who.int/handle/10665/117702