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Ceftriaxone versus ampicillin/cloxacillin as antibiotic prophylaxis in elective caesarean section / Ahmed, E.T.S.;Mirghani, O.A.;Gerais, A.S.;Adam, I.

Tác giả : Ahmed, E.T.S.;Mirghani, O.A.;Gerais, A.S.;Adam, I.

Năm xuất bản : 2004

Chủ đề : 1. Ampicillin. 2. Apgar Score. 3. Cross Infection. 4. Endometritis. 5. Fever. 6. Hospitals, Teaching. 7. Incidence. 8. Pregnancy.

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Tóm tắt :

277-282 We carried out a prospective, r and omized, controlled clinical trial to evaluate the clinical efficacy of ceftriaxone and ampicillin/cloxacillin prophylaxis in decreasing the frequency of post-caesarean section infection-related morbidity. Two hundred patients randomly received either ceftriaxone [single dose] or ampicillin/cloxacillin [3 doses] intravenously at induction of anaesthesia. There was no statistical difference in incidence of endometritis [P = 0.34], wound infection [P = 0.44], or other febrile morbidity [P = 0.5]. Eleven babies had a low Apgar score [< 8] in the ceftriaxone group and 13 in the ampicillin/cloxacillin group [P = 0.82].There were 2 perinatal deaths in each group. One dose of ceftriaxone was as effective as ampicillin/ cloxacillin in preventing post-caesarean section complications and is easier to administer

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https://iris.who.int/handle/10665/119409